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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLK1
All Species:
10.61
Human Site:
S181
Identified Species:
23.33
UniProt:
Q9UKI8
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKI8
NP_036422.3
766
86700
S181
S
H
S
H
S
T
P
S
S
S
V
R
P
N
S
Chimpanzee
Pan troglodytes
XP_001141231
787
89005
P181
Q
G
G
N
G
S
S
P
V
R
G
I
P
P
A
Rhesus Macaque
Macaca mulatta
XP_001084145
718
81923
I181
A
A
L
E
S
N
K
I
Q
D
L
E
K
K
E
Dog
Lupus familis
XP_535959
766
86670
S181
S
H
S
H
S
T
P
S
S
S
V
R
P
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0V0
766
86605
S181
S
H
S
H
S
T
P
S
S
S
V
R
P
N
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515053
718
81881
N181
A
A
L
E
S
N
K
N
Q
D
L
E
K
K
E
Chicken
Gallus gallus
XP_426581
764
86358
V182
S
H
S
A
P
S
S
V
R
Q
N
S
P
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q90ZY6
756
85436
Q182
A
P
G
A
I
V
R
Q
N
S
S
S
P
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624065
793
90042
Q209
A
G
S
M
V
S
K
Q
V
Q
V
R
P
T
N
Nematode Worm
Caenorhab. elegans
P34314
965
109255
S226
S
A
Q
Q
P
Q
Q
S
S
A
A
L
Q
H
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39238
688
78131
Q181
S
Q
L
D
A
S
D
Q
K
D
F
R
P
D
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.5
99.4
N.A.
98.1
N.A.
N.A.
91.5
94.1
N.A.
83.2
N.A.
N.A.
46.4
37.9
N.A.
Protein Similarity:
100
97.3
93.7
99.7
N.A.
99.2
N.A.
N.A.
92.8
95.8
N.A.
89.4
N.A.
N.A.
61.2
50.8
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
100
N.A.
N.A.
6.6
26.6
N.A.
20
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
100
26.6
20
100
N.A.
100
N.A.
N.A.
26.6
40
N.A.
33.3
N.A.
N.A.
46.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
28
0
19
10
0
0
0
0
10
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
0
28
0
0
0
10
0
% D
% Glu:
0
0
0
19
0
0
0
0
0
0
0
19
0
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
19
19
0
10
0
0
0
0
0
10
0
0
0
10
% G
% His:
0
37
0
28
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
10
0
0
10
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
28
0
10
0
0
0
19
19
0
% K
% Leu:
0
0
28
0
0
0
0
0
0
0
19
10
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
19
0
10
10
0
10
0
0
28
10
% N
% Pro:
0
10
0
0
19
0
28
10
0
0
0
0
73
10
10
% P
% Gln:
10
10
10
10
0
10
10
28
19
19
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
10
10
0
46
0
0
0
% R
% Ser:
55
0
46
0
46
37
19
37
37
37
10
19
0
10
37
% S
% Thr:
0
0
0
0
0
28
0
0
0
0
0
0
0
19
0
% T
% Val:
0
0
0
0
10
10
0
10
19
0
37
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _